ГОРЕ

доц. д-р Биљана Миова

Image descriptionName: Biljana Miova
Date and place of birth: 07. 03. 1973, Veles, Republic of Macedonia
Citizenship/Nationality Macedonian
Marital Status:
Office address: Institute of Biology, Faculty of Natural Sciences and Mathematics, Arhimedova 6, PO Box 162, “Sv. Kiril i Metodij” University, Skopje, Republic of Macedonia
Home Address: Vidoe Smilevski – Bato, 15/2- 28, 1000, Skopje, Republic of Macedonia
Telephone: Office: + 389 2 3249 602, Mob: + 389 70 315 989
Fax: + 389 2 228 141
E-mail: bmiova@pmf.ukim.edu.mk bmiova@yahoo.com
Language skills: English, French, Serbian and Macedonian

Education – degrees awarded:
1991-1996, Engeneer of Biochemistry, Faculty of Natural Sciences and Mathematics, Institute of Biology, “Sv. Kiril i Metodij” University, Skopje, Republic of Macedonia.
1997-2003, Post graduated Master Study at the Department of Biochemistry, Faculty of Natural Sciences and Mathematics, Institute of Biology, “Sv. Kiril i Metodij” University, Skopje, Republic of Macedonia.

Title of Master Thesis:
“Influence of high environmental temperature on some enzymes and substrates of carbohydrate metabolism in different tissue in rats” 2004-2010, Doctoral Study at the Institute of Biology, “Sv. Kiril i Metodij” University, Skopje, Republic of Macedonia.

Title of Doctoral Thesis:
“Acclimation to moderate heat and gene expression of key enzymes in carbohydrate metabolism in nicotinamide / streptozotocin diabetic rats”

Professional Experience:
1997-2001: Research postgraduate student at the Faculty of Natural Sciences and Mathematics
2001-2003: Research assistant (Comparative physiology, Animal ecophysiology, Physiology of work) Faculty of Natural Sciences and Mathematics
2003 up to date: Teaching Assistant (Comparative physiology, Animal ecophysiology, Physiology of work, Enzymology), Faculty of Natural Sciences and Mathematics, Skopje.

Professional visits & study tours:
1993 to 1997: As an active member of IAESTE realized 3 exchange trainings in Slovenia, Germany and Hungary.
2006 - short term (two weeks) stay in the laboratories of INSERM U885, Lyon, France,
2007 - short term (3 mounts) stay in the laboratories of INSERM U885, Lyon, France.

Professional membership:
Member of the Macedonian Society of Physiological Sciences.

Teaching experience as Assistant Teacher:
• Comparative physiology (Institute of Biology, Faculty of Natural Sciences and Mathematics)
• Animal ecophysiology (Institute of Biology, Faculty of Natural Sciences and Mathematics)
• Physiology of work (Institute of Biology, Faculty of Natural Sciences and Mathematics)
• Enzymology (Institute of Biology, Faculty of Natural Sciences and Mathematics)

Participation in research projects:
• 1997-2000: “Investigation of the activities of some key enzymes and substrates from carbohydrate metabolism in the liver of rats”, supported by Ministry of Education and Science of R. Macedonia
• 2001-2002: “Distribution of heavy metals in different tissue in reptilia and amphibia in the Veles region”, supported by Ministry of Environment and Urban Planning of R. Macedonia
• 2001-2002: “Distribution of heavy metals in different tissue in reptilia and amphibia in the Bitola region”, supported by Ministry of Environment and Urban Planning of R. Macedonia
• 2000-2003: "The influence of thyroid state on carbohydrate metabolism in rats exposed to high environmental temperature”, supported by Ministry of Education and Science of R. Macedonia
• 2000-2003: "The influence of diabetes on carbohydrate metabolism and development of angiopathy in rats exposed to high environmental temperature", supported by Ministry of Education and Science of R. Macedonia
• 2006-2009: “Metabolic and hormonal disturbances in diabetic rats acclimated to moderate hyperthermic environment”, supported by Ministry of Education and Science of R. Macedonia

Scientific experience:
• Enzymatic analyses (spectrofotometric);
• ELISA methods;
• Isolation of RNA;
• Semiquantitative RT-PCR;
• Real-time PCR;
• Western blot analyses.

List of publications:
List of Publications in Scientific Journals:
1. Dinevska-Kjovkarovska, S., Mitev, S., Miova, B. (2000): Influence of thyroid hormones on the activity of hepatic glucose-6-phosphatase in male rats acclimated to high environmental temperatures. Ann. Rev. Fac. Natural Sciences, Skopje, Vol. 53/54, 103-112
2. Dinevska-Kjovkarovska, S., Miova, B., Mitev, S. (2001): Glycogen phosphorylase a activity and liver glycogen content during fasting in rats acclimated to high environmental temperature. Ann. Rev. Fac. Natural Sciences, Skopje, Vol. 53/54, 94-102
3. Roganovic-Zafirova, D., Panov, S., Stankovic, A., Miova, B., Jovceva, T. (2002): Vitellogenin induction in several fish species from Lake Prespa as indicator of xenoestrogenic exposure. Contributions, Sec. Biol. Med. Sci., MASA, XXIII, 1-2, p. 61-77
4. Mitev, S., Dinevska-KjovkarovskaS. and Miova, B (2005): The effect of acclimation to high environmental temperature on the activity of hepatic glycogen phosphorylase (a+b and a), liver glycogen content and blood glucose level. Journal of Thermal Biology 30, 563-568
5. Dinevska-Kjovkarovska, S., Mitev, S. Miova, B (2006): Liver fructose-1,6-bisphosphatase, PEPCK and PK activity in fasted rats during acclimation to high environmental temperature. Periodicum Biologorum, Vol 108, Issue 5, pp. 603-607
6. Miova, B., Dinevska-Kjovkarovska, S., Mitev, S. and Dervisevik, M. (2008): The effect of fasting on glycogen metabolism in heat-acclimated rats. Archives of Biological Sciences, 600 (1), 49-58
7. Dinevska-Kjovkarovska, S., Miova, B., Mitev, S and Popeska, Z. (2006/2007): Some aspects of hepatic carbohydrate metabolism in heat-acclimated diabetic rats. Biologia Macedonica, 59/60, 37-51
8. Miova, B., Dinevska-Kjovkarovska, S. and Mitev, S. (2008): Changes in carbohydrate metabolism during acclimation to a moderate hyperthermic environment in rats. Journal of Basic and Clinical Physiology and Pharmacology, Vol. 19, No. 1. 65-87
9. Suzana Dinevska-Kjovkarovska, Teuta Guladin, Biljana Miova, Slavco Mitev, Katerina Gerazova. Changes in the hypothalamo-pituitary-adrenocortical and hypothalamo-pituitary-thyroid axes in diabetic rats acclimated to moderate hyperthermic environment. Journal of Thermal Biology 34 (2009) 200–205
10. Gjoshe Stefkov, Svetlana Kulevanova, Biljana Miova , Suzana Dinevska –Kjovkarovska. Knud Josefsen, Anna K. Jager and Per Molgaard. Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. Submitted

Published contributions to academic conferences::
1. Mitev, S., Dinevska-Kovkarovska, S., Buzalkov, R. and Miova, B. (1998): Vlijanie na gladuvaweto vrz aktivnosta na glikogen fosforilza i glukoza-6-fosfataza vo crn drob kaj staroci aklimirani na visoka nadvore{na temperature. 2. Congress of the biologist in Macedonia, Aps. 78, Ohrid 1998
2. Dinevska-Kovkarovska, S., Mitev, S., Miova, B.. (2000): Hepatic piruvate kinase activity in thyroidectomized heat-acclimated rats. 18th Internacional Congress of Biochemistry and Molecular Biology, Beyond the Genome, 16-20 July 2000, Birmingham. Abstract Book, 182
3. Mitev, S., Dinevska-Kovkarovska, S., Miova, B. (2001): Glycogen phosphorylase activity during acclimation to high environment temperature in fed and fasted rats. Procced. Of the Australian Physiological and Pharmacologycal Society, Vol. 32, 2, Supplement 1:Internaional Thermal Physiology symposium, Wollongong, Australia, september 2nd -6th, 2001, 106P
4. Jurhar-Pavlova, M., Trajkov, D., Pavkovik, M., Petlichkovski, A., Arsov, T., Jankova, R., Dinevska-Kjovkarova, S., Miova, B., Mitev, S., Spiroski, M. (2001): Imunoglubulin classes (IgA, IgG, IgM) in serum of rats during acclimation to elevated ambient temperature. 3rd Balkan Congress of Immunology, Octomber 30- November 1, 2001. Athens, Greece
5. Jurhar-Pavlova, M., Dinevska-Kjovkarova, S., Trajkov, D., Pavkovik, M., Petlichkovski, A., Miova, B., Mitev, S., Spiroski, M. (2001): Changes in four subclasses of rat immunoglobulin IgG during acclimation to elevated ambient temperature. XIXth Congress of the European Academy of Allergology and Clinical Immunology, July 1-5, 2001, Lisbon, Portugal
6. Dinevska-Kovkarovska, S., Mitev, S., Miova, B., Baniska, A. (2002): T4, fT4, T3 and fT3 in rats durung acclimation to high environmental temperature. 10TH Meething of the Balkan Clinical laboratory Federation, September, 2002, Ohrid, R. Macedonia
7. Mitev, S., Dinevska-Kovkarovska, S., Miova, B., Baniska, A. (2002): Changes in the level of cholesterol, triacylglyceroles and free fatty acids in rats during exposition to high environmental temperature. 10TH Meething of the Balkan Clinical laboratory Federation, September, 2002, Ohrid, R. Macedonia
8. Dinevska-Kovkarovska, S, Mitev, S., Miova, B. (2003): Glucose-6-phosphatase activity during acclimation to high environment environment temperature in fed and fasted rats. 8th Croatian Biological Congress with Inter. Part., 27sept-2oct, Zagreb, Croatia. Proceedings, pp.209
9. Mitev, S., Dinevska-Kovkarovska, S., Miova, B (2003): Activity of hepatic pyruvate kinase and phosphoenolpyruvate carboxykinase in rats during the acclimation to hyperthermic environment. 8th Croatian Biological Congress with Inter. Part., 27sept-2okt, Zagreb, Croatia. Proceedings, pp. 220
10. S. Dinevska-Kovkarovska, S. Mitev, B. Miova (2003): The effect of high environmental temperature on hepatic glucose-6-phosphatase activity and glucose-6-phosphate content in female diabetic rats. 11th Meeting of BCLF, 24-27 Sept, Belgrade, Yugoslavia. Yugoslav Med Biochem 22, (suppl. 2), 121, 2003
11. Miova, B., Dinevska-Kovkarovska, S. Mitev, S. (2003): Hepatic glycogen phosphorylase activity in diabetic and insulin-treated heat-acclimated rats. 11th Meeting of BCLF, 24-27 Sept, Belgrade, Yugoslavia. Yugoslav Med Biochem 22, (suppl. 2), 118, 2003
12. Gjuladin, T., Dinevska-Kovkarovska, S., Miova B., Domazetovska, S. (2003): Influence of high environmental temperature on blood glucose level, HBA1c and insulin concentration in female diabetic rats. 11th Meeting of BCLF, 24-27 Sept, Belgrade, Yugoslavia. Yugoslav Med Biochem 22, (suppl. 2), 120, 2003
13. Dinevska-Kovkarovska, S. Mitev, S., Miova B. (2004): Renal glycogen content and glucose-6-phosphatase activity in heat-acclimated diabetic and insuli-treated rats. 12th Meeting of Balkan Clinical Laboratory Federation, 15-18 Sept, 2004, Romania. Abstract book, 93
14. Dinevska-Kovkarovska, S. Mitev, S., Miova B.: The effect of fasting on glycogen phosphorylase activity, glucose-1-phosphate and glycogen content in the liver of heat-acclimated rats. First Integrated Meeting on Thermal Physiology and Pharmacology of Thermoregulation, Rhodes, Greece, October 10-15, 2004. Abstract book, pp. 174
15. Miova, B., Dinevska-Kovkarovska, S. Mitev, S.: Glucose-6-phosphatase activity, glucose-6-phosphate and glycogen content in liver of rats during acute and chronic exposure to high environmetal temperature. First Integrated Meeting on Thermal Physiology and Pharmacology of Thermoregulation, Rhodes, Greece, October 10-15, 2004. Abstract book, pp. 174
16. Dinevska-Kovkarovska, S. Mitev, S., Miova B. (2005): Influence of heat acclimation on liver glycogen metabolism in fasted rats. 1st Congress of the physiological sciences of Serbia and Montenegro with internacional participation. 9 -12 Nov, Beograd. Abstract book, 205
17. Miova, B., Kjovkarovska- Dinevska S., Mitev, S. (2005): Some hormonal changes in diabetic-heat acclimated rats. 1st Congress of the physiological sciences of Serbia and Montenegro with internacional participation. 9 -12 Nov, Beograd. Abstract book, 204
18. Mitev, S. and Miova, B. and Kjovkarovska- Dinevska S. (2005): Influence of thyroid hormones on hepatic glucose-6-phosphatase and glycogen phosphorylase activity in rats acclimated to high environmental temperature. 1st Congress of the physiological sciences of Serbia and Montenegro with internacional participation. 9 -12 Nov, Beograd. Abstract book, 206
19. Domazetovska, S., Dinevska-Chovkarovska, S., Miova, B. (2006): The effect of high environmental temperature and diabetes on enzymes and lipid status in rats. 14th Meeting of Balkan Clinical Laboratory Federation, 29-30.09, Sofia, Balkan Journal of Clinical Laboratory, XIII, O6, 1
20. Dinevska-Kjovkarovska S., Miova B., Mitev S. (2006): The effects of high environmental temperature on the glycogen metabolism depending on metabolic state in female rats. International Society for Adaptive Medicine. VIII World Congress, 21-24 June, Moscow, Russia
21. Dinevska – Ќovkarovska, S., Miova, B., Melovski, Lj., Hristovski, S., Sterijovski, B., Janevski, R., Stamatovski, B. (2007): Comparative analysis for presence of heavy metals in different tissues of Anura in Skopje and Veles and their surroundings. III Congress of ecologists of the Republic of Macedonia with International Participation, 06-09 Octomber Struga, Abstract book 149
22. Gjuladin, T., Dinevska – Ќovkarovska, S., Miova,B., Ismaili, M. and Abazi, A. Influence of high environmental temperature on the level of some hormones in rats (Ref. No. MT12-Op- 1116) in International conference on Environment: Survival and Sustainability. Nicosia, 19-23 Feb. 2007
23. Miova, B., Dinevska-Kjovkarovska, S., Mitev, S., Mithieux, G., Rajas, F. and Zitoun, C. (2008): Glucose-6-phosphatase activity and gene expression in nicotinamide / streptozotocin-diabetic rats. Effect of acclimation to moderate heat. 5th World Congress on Prevention of Diabetes and its Complications. June 1-4, Helsinki, Finland
24. Miova, B., Dinevska-Kjovkarovska, S., Mithieux, G., Rajas, F., Mitev, S., Panov, S. and Zitoun, C. Altered glucose metabolism and gene expression in nicotinamide / streptozotocin heat acclimated diabetic rats. 17th Meeting of Balkan Clinical Laboratory Federation, Sept. 16-19, Ohrid, 2009
25. Dervisevic, M., Miova, B., Dinevska-Kjovkarovska, S., Mitev, S., Shushleski, D The effect of shrot- and long-term heat acclimation on carbohydrate metabolism in rat heart. 17th Meeting of Balkan Clinical Laboratory Federation, Sept. 16-19, Ohrid, 2009
26. Gerazova, K., Miova, B., Dinevska-Kjovkarovska, S., Mitev, S., Velkovski, M. The effect of acute hyperthermic stress and nicotinamide treatment over hepatic carbohydrate metabolism in streptozotocin-diabetic rats. 17th Meeting of Balkan Clinical Laboratory Federation, Sept. 16-19, Ohrid, 2009
27. Miova, B., Dinevska-Kjovkarovska, S., Panov, S., Mitev, S. Altered gene expression of HSP72 mRNA in heat-acclimated diabetic rats treated with nicotonamide. 6th World Congress on Prevention of Diabetes and its Complications (WCPD 2010), Dresden, Germany on April 8-11, 2010
28. Gerazova, K., Miova, B., Dinevska-Kjofkarovska, S., Mitev, S., Velkovski, M. Effect of the Acute Hypethermic Stress and Nicotinamide Treatment Over Glucose Metabolism in STZ-rats. 6th World Congress on Prevention of Diabetes and its Complications (WCPD 2010), Dresden, Germany on April 8-11, 2010